- Localized intrapulmonary mesothelioma presenting with a pulmonary massTing Wang, Meng Cui, Asmitananda ThakurIndian Journal of Pathology and Microbiology 2019 62(4):636-638
- Invasive, gangrenous mucormycosis of arm: A fatal opportunistic infection in a highly immunocompromised hostVijayanth Kanagaraju, Venkatesh Kumar Narayanasamy, Sanjeev Sukumaran, Udaya Moorthy, V Shyam Sundar, S Vidhya LakshmiIndian Journal of Pathology and Microbiology 2019 62(4):618-620 Opportunistic fungal infections occur predominantly in immunocompromised (IC) patients. Mucormycosis has the highest mortality among fungal infections. The organism is ubiquitous in its presence. The infection is commonly acquired by inhalation of fungal spores or
- p16 as an independent marker for detection of high-risk HPV in oral submucous fibrosis and oral squamous cell carcinomaArchana Sudhakaran, Kaveri Hallikeri, Biji BabuIndian Journal of Pathology and Microbiology 2019 62(4):523-528 Background: An alarming increase in incidence of high-risk human papillomavirus (HPV) positive tumors in head and neck squamous cell carcinoma (HNSCC) by 25% and 70% in oropharyngeal HNSCC cannot be ignored. The early oncogenes of HPV, E6, and E7 play a key role in carcinogenesis. HPV associated tumors have a better clinical outcome
- Primary epithelial splenic cyst: A rare encounterPooja Sharma Kala, Sheenam Azad, Trisha Sharma, Seema AcharyaIndian Journal of Pathology and Microbiology 2019 62(4):605-607 Splenic cysts are rare with an overall incidence of 0.07% in a large autopsy series and 0.5% among all the splenectomies done. The parasitic splenic cysts, usually caused by Echinococcus granulosus, account for 60% of all primary splenic cysts. The primary epithelial cysts account for 10% of all splenic cysts. We report
- Omics data-driven analysis identifies laminin-integrin-mediated signaling pathway as a determinant for cell differentiation in oral squamous cell carcinomaSpoorti Kulkarni, Riaz Abdulla, Maji Jose, Soniya Adyanthaya, DA B Rex, Arun H Patil, Sneha M Pinto, Yashwanth SubbannayyaIndian Journal of Pathology and Microbiology 2019 62(4):529-536 Background: In recent years, high-throughput omics technologies have been widely used globally to identify potential biomarkers and therapeutic targets in various cancers. However, apart from large consortiums such as The Cancer Genome Atlas, limited attempts
- Primary actinomycosis of anterior abdominal wall: A rare occurrence, diagnosed on fine needle aspiration cytologyMona Agnihotri, Kanchan Kothari, Leena NaikIndian Journal of Pathology and Microbiology 2019 62(4):629-630 Actinomycosis, a chronic suppurative and granulomatous infection, is caused by Actinomyces israeli. The common clinical presentations are cervicofacial, abdominal, and thoracic regions. Abdominal wall actinomycosis following pelvic or intraperitoneal involvement is known, but isolated abdominal wall involvement is extremely rare and can
- Collagen fibers in oral submucous fibrosis - A polarizing microscopy study using two special stainsRoquaiya Nishat, Harish KumarIndian Journal of Pathology and Microbiology 2019 62(4):537-543 Background: Oral submucous fibrosis (OSMF), a well-recognized oral potentially malignant disorder, results due to increased collagen production and reduced collagen degradation. Aims and Objectives: To qualitatively compare the staining properties of collagen in OSMF using two special stains based on their birefringent property using polarizing micros
- Acute myeloid leukemia presenting as fissure-in-ano: A unique case of histologically proven anodermal leukemia cutisKavita Gaur, Vandana Puri, Manjula Jain, Sunaina Hooda, Sunita Sharma, Manoj AndleyIndian Journal of Pathology and Microbiology 2019 62(4):645-646
- Risk of malignancy in Thyroid “Atypia of undetermined significance/Follicular lesion of undetermined significance” and its subcategories – A 5-year experienceAbha Thakur, Haimanti Sarin, Dilpreet Kaur, Deepak SarinIndian Journal of Pathology and Microbiology 2019 62(4):544-548 Context: Atypia of undetermined significance/Follicular lesion of undetermined significance [AUS/FLUS] is a heterogeneous category with a wide range of risk of malignancy [ROM] reported in the literature. The Bethesda system for reporting thyroid cytopathology [TBSRTC], 2017 has recommended subcategorization of AUS/FLUS. Aim
- Tale of a mermaidPranjali Vasisht, Manoj G Madakshira, Nandita Kakkar, Veenu Singla, Vanita JainIndian Journal of Pathology and Microbiology 2019 62(4):611-613 Sirenomelia is a rare congenital anomaly characterized by the presence of a median single lower appendage. The affected fetus is popularly referred to as a “Mermaid baby,” due to the uncanny resemblance to the fictious fable character. The manifestation is a result of the merger of the lower limbs with
- Loss of c-Cbl expression correlates with de-differentiation status and lymphatic metastasis in gastric cancerChuchu Chen, Yi Hui, Yunzhao Chen, Chengjia Qian, Minxuan SunIndian Journal of Pathology and Microbiology 2019 62(4):549-555 Context: C-Cbl is an important negative regulator of the cell signaling that acts as an adaptor protein and E3 ubiquitin ligase. The role of c-Cbl in development and regulation of human cancer has aroused intensive attention. Aims: In this study, we aimed to assess the correlation between the expression of c-Cbl and cli
- Solid pseudopapillary neoplasm of pancreas metastasizing to spleen in a post menopausal femaleTanisha Singla, Charanjeet Ahluwalia, Gaurav Singla, Sachin Kolte, Swati Singla, Rashmi AroraIndian Journal of Pathology and Microbiology 2019 62(4):624-626
- Clinicopathological profile of hepatoblastoma: An experience from a tertiary care center in IndiaB Archana, J Thanka, Latha M Sneha, J Julius Xavier Scott, M Arunan, Prakash AgarwalIndian Journal of Pathology and Microbiology 2019 62(4):556-560 Background: Hepatoblastoma is the most common primary hepatic malignancy in the pediatric population. Advances in pathological evaluation, imaging, risk stratification, neo-adjuvant chemotherapy, and surgery including transplantation have improved survival of these children in the western countrie
- EBV positive mucocutaneous ulcer of palate: A mimicker of malignancyDeepa Goel, Mandeep SinghIndian Journal of Pathology and Microbiology 2019 62(4):632-634
- The role of p53, Ki-67 and laminin expression in the differential diagnosis of keratoacanthoma and well-differentiated SCCGulay Turan, Eren Altun, Figen Aslan, Ozgur KulahciIndian Journal of Pathology and Microbiology 2019 62(4):561-565 Introduction: We have aimed to evaluate the difference between the expression of p53, Ki-67, and laminin in keratoacanthoma and well-differentiated SCC (SCC) and to determine its importance in differential diagnosis. Methods: This study totally included 46 cases consisting of 23 cases with keratoacanthoma and 23 with SCC. As well
- Primary melanoma of cecum: A diagnostic challengeNouha Mahmood Alwani, Sohaila Fatima, Balkur Krishnamoorthi Adiga, Nazima HaiderIndian Journal of Pathology and Microbiology 2019 62(4):641-642
- Morphological characterization and molecular profiling of malignant pericardial effusion in patients with pulmonary adenocarcinomaBing Zhou, Lin Li, Dayou Shi, Tao Jiang, Guohui Xue, Jianping XiongIndian Journal of Pathology and Microbiology 2019 62(4):566-571 Context: Malignant pericardial effusions (MPCEs) is a common complication observed in advanced pulmonary adenocarcinoma. In such cases, investigating molecular alterations can have significant therapeutic implication in determining anticancer drugs. Aim: The objective was to evaluate the significance of cell block
- From Editor's deskRanjan AgrawalIndian Journal of Pathology and Microbiology 2019 62(4):521-522
- Evaluation of high-fluorescence body fluid (HF-BF) parameter as a screening tool of malignancy in body fluidsLoveena Rastogi, Jasmita Dass, Vandana Arya, Jyoti KotwalIndian Journal of Pathology and Microbiology 2019 62(4):572-577 Introduction: Automated body fluid (BF) analysis is gradually replacing the traditional methods of cell counting in all BFs. This study was done to analyze the high-fluorescence (HF)-BF parameter generated on Sysmex XN-1000 and study its correlation with the presence of malignant cells in the body fluids. A correlation betw
- “Endolymphatic sac tumour”: A case report with review of literatureB Rajeshwari, Salapathi Shanmugam, Niamath Sadiya, Ghosh Mitra, B ChendilnathanIndian Journal of Pathology and Microbiology 2019 62(4):608-610 Endolymphatic sac tumour (ELST) is a non-metastasizing low grade adenocarcinoma of endolymphatic sac origin. It is also known as Heffner tumour, low grade adenocarcinoma of endolymphatic sac origin and aggressive papillary middle ear tumour. These tumours are closely associated with Von Hippel Lindau (
- Role of procalcitonin, Il-6 and C- reactive protein in suspected cases of sepsisShiwangi Sharma, Nandini DuggalIndian Journal of Pathology and Microbiology 2019 62(4):578-581 Objectives: To study the role of serum procalcitonin as a diagnostic biomarker in sepsis and to compare it with other sepsis markers (IL-6, CRP) in patients of suspected sepsis. Materials and Methods: A total of 80 patients were included in this study from ICU and each patient was investigated for serum Procalcitonin, Interleukin-6 and C-reactive pr
- FLI1 and MIC2 expression in precursor B-lymphoblastic leukemia with Burkitt-like morphology and extensive extramedullary involvement: A diagnostic challenge in pediatric small round cell tumorNupur Das, Deepshi Thakral, Geetika Singh, Ankit Malhotra, Ravi Hari Phulware, Ajay Gogia, Ritu GuptaIndian Journal of Pathology and Microbiology 2019 62(4):614-617 Pediatric small round cell tumors (PSRCTs) constitute a large proportion of childhood malignancies with overlapping diagnostic and clinical features but radically different therapies. Here, we report a case of 16-year-old male child presenting with diffuse abdominal and mediastinal
- Metastatic hepatocellular carcinoma to the parotid gland: A diagnostic dilemma with review of the literatureHema Malini Aiyer, Sanjay Deb, Garima RawatIndian Journal of Pathology and Microbiology 2019 62(4):582-585 Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy and is a leading cause of cancer-related death worldwide. It has a very aggressive clinical course, with a mean survival rate of much less than a year if left untreated. Here, we present a case of a 68-year-old male with progressively enlarging painful right fac
- A case report of Nocardia cyriacigeorgica presenting as cellulitis with multiple discharging sinusesArchana Bora, Laxmi Rathore, Prabhat K Khatri, CS ChattopadhyayIndian Journal of Pathology and Microbiology 2019 62(4):621-623 Nocardia spp. are filamentous Gram positive bacteria that are ubiquitous soil saprophytes. The majority of nocardial infections occur in severely immunocompromised patients who are particularly susceptible to pulmonary disease and dissemination. Extrapulmonary nocardiosis is relatively common and can occur through hem
- Primary epiglottic follicular variant of peripheral T-cell lymphomaJienan Kong, Lin Zhong, Xue Gao, Wenjing Qi, Lizhi Zhang, Zhenhua LinIndian Journal of Pathology and Microbiology 2019 62(4):586-588 The follicular variant of peripheral T-cell lymphoma, not otherwise specified, is very rare. Primary epiglottic follicular variant of peripheral T-cell lymphoma is extremely rare in clinical practice. Here, we report the first case of a follicular variant of peripheral T-cell lymphoma not otherwise specified in
- Incidentally detected acalculous tubercular cholecystitis: A rare case report with a comprehensive review of literatureDimple Chaudhary, Navpreet Kaur, Shramana Mandal, Nita Khurana, CB SinghIndian Journal of Pathology and Microbiology 2019 62(4):627-628
- Fever work-up unfolds a rare diagnosis of native valve endocarditis caused by Mycobacterium abscessusAnita Sharma, Irneet Mundi, Karun Behal, Navreet Kaur, Pooja Singh, Manish MahantIndian Journal of Pathology and Microbiology 2019 62(4):589-591 Endocarditis caused by Mycobacterium abscessus is rare and often missed without appropriate blood cultures. It does not respond to standard antitubercular treatment and is also resistant to many other antibiotics. The course of the disease may be indolent and often results in a fatal outcome. Accurat
- Cavernous hemangioma of uvula: A rare siteSharada Rane, Mayur V Parkhi, Gourav Agrawal, Ashwini GhodkeIndian Journal of Pathology and Microbiology 2019 62(4):631-632
- Sympathetic ophthalmia with incidental finding of chicken pox supported by histopathology and immunohistochemistryDipankar Das, Subramanium Krishnakumar, Jyotirmay BiswasIndian Journal of Pathology and Microbiology 2019 62(4):592-594 Sympathetic ophthalmia (SO) is a rare bilateral diffuse granulomatous panuveitis that occurs in few days to several years after penetrating injury. This intraocular inflammation can occur in any age group without a sex predilection. Pathology and immunohistochemistry-supported evidence is important to know the disease in a b
- Carancular mass- Always take with a pinch of salt!Divya Basa, Pasyanthi Balijepalli, Kaustubh MulayIndian Journal of Pathology and Microbiology 2019 62(4):635-636
- Type I pleuropulmonary blastoma presenting as congenital pulmonary airway malformation: A report of two casesKalpana Kumari, Moanaro Longchar, Ganganath Gunathilaka, Priyanka Narange, Sandeep Aggarwal, Sudheer AravaIndian Journal of Pathology and Microbiology 2019 62(4):595-598 Pleuropulmonary blastoma (PPB) is a rare aggressive intrathoracic tumor which is believed to originate from embryonic uncommitted lung mesenchymal cells, which are important for developing the lung. Type I PPB is cystic, type II is cystic and solid, while type III is predomin
- Extensive gastrointestinal amyloidosis due to multiple myeloma mimicking inflammatory bowel disease in a young maleArvind Ahuja, Vishal Sharma, Minakshi Bhardwaj, Sadhna Marwah, Sandeep LamoriaIndian Journal of Pathology and Microbiology 2019 62(4):638-640
- Cardiac myxoma with cartilaginous differentiation-An uncommon variant presented as mitral stenosisSunil V Jagtap, Pravin Salunkhe, Avinash Mane, Sujata Kumbhar, Purva Mayekar, Saswati BoralIndian Journal of Pathology and Microbiology 2019 62(4):599-601 The estimated incidence of primary cardiac tumors is extremely rare. Among it, cardiac myxoma represents the most common benign cardiac tumor constituting about 80% of cases. We are presenting a 30–year-old female with large left atrial myxoma. She was presented with severe dyspnea, palpita
- Recurrent monophasic synovial sarcoma in a childPriyanka Maity Chaudhuri, Nelofar Islam, Mou Das, Uttara Chatterjee, Chhanda DattaIndian Journal of Pathology and Microbiology 2019 62(4):643-645
- Myeloid sarcoma of bile ducts presenting as obstructive jaundice – A case reportAyushi Agarwal, Tina Dadu, VP Bhalla, Veena MalhotraIndian Journal of Pathology and Microbiology 2019 62(4):602-604 Myeloid sarcoma is an extra medullary manifestation of acute myeloid leukemia (AML). Primary involvement of the biliary tract with myeloid sarcoma presenting as obstructive jaundice without evidence of leukemia is very rare. Here we present a case of 72 year old lady, who initially presented with features of biliary obstruction
- Catechism (Quiz 6)Bharat RekhiIndian Journal of Pathology and Microbiology 2019 62(4):647-649
Journal of Postgraduate Medicine : 2014 - 60(3)
- Occult scar carcinoma of the lung with overt liver metastases and high serum CA 19-9 levelsYY Lin, SF ChoJournal of Postgraduate Medicine 2019 65(4):251-252
- Heterozygous lys169Glu mutation of glucokinase gene in a Chinese family having glucokinase-maturity-onset diabetes of the young (GCK-MODY)W Zhou, M Chen, H Zhou, Z ZhangJournal of Postgraduate Medicine 2019 65(4):241-243 We report a 24-year-old female with early-onset and persistent mild fasting hyperglycemia due to glucokinase-maturity-onset diabetes of the young (GCK-MODY). A c.505A>G (p. Lys169Glu) missense mutation of the GCK gene was identified. In silico analysis indicated that the mutation affected a conserved amino acid and is disease-causing. This report describes GCK-MO
- Does the precept of role and religious belief affect stress in Indian doctors?MS BhatiaJournal of Postgraduate Medicine 2019 65(4):197-198
- Pigmented villonodular synovitis: Four pediatric cases and brief review of literatureS Turkucar, B Makay, H Tatari, E UnsalJournal of Postgraduate Medicine 2019 65(4):233-236 Pigmented villonodular synovitis (PVNS) is a rare benign disorder of a joint which affects its synovium, tendon sheaths and bursas. While most cases of PVNS are adult patients aged between 20-50 years, few afflicted children have also been reported. Clinical signs of PVNS are insidious and non-specific. Pain, swelling and stiffness are the major symptoms.
- The enormous economic burden of slow learners: A wake up callM ParakhJournal of Postgraduate Medicine 2019 65(4):199-200
- Retroperitoneal gossypiboma mimicking renal tumor in a postrenal transplant patient: A diagnostic challengeS Rajaian, P Murugavaithianathan, K Krishnamurthy, L MurugasenJournal of Postgraduate Medicine 2019 65(4):247-248
- Job stress and satisfaction in faculty of a teaching hospital in south India: A cross-sectional surveyA Chichra, A Abhijnhan, P TharyanJournal of Postgraduate Medicine 2019 65(4):201-206 Background: There are multiple economic, psychological, and physical consequences of high job stress, low job satisfaction and burnout in faculty of a teaching hospital in South India. Data from developing countries on these domains are sparse. Materials and Methods: In a cross-sectional study we assessed the prevalence and sources of perceived job stress, job
- Cystic fibrosis revisitedH Kulkarni, S Kansra, S KarandeJournal of Postgraduate Medicine 2019 65(4):193-196
- Statins and gastroesophageal reflux disease: A meta-analysisK Wijarnpreecha, P Panjawatanan, L Leelasinjaroen, P UngprasertJournal of Postgraduate Medicine 2019 65(4):207-211 Background/Objectives: Gastroesophageal reflux disease (GERD) is one of the common gastrointestinal disorders worldwide. Recent epidemiologic studies have suggested that use of statins may lower the risk of GERD although the results from different studies were inconsistent. This systematic review and meta-analysis were conducted wi
- Retropharyngeal ectopic parathyroid adenoma versus lymph node: Problem solving with CT neck angiogramPP Batchala, PK RehmJournal of Postgraduate Medicine 2019 65(4):237-240 A 66-year-old female underwent preoperative evaluation for primary hyperparathyroidism. Ultrasound (US) neck and technetium (Tc)-99m-sestamibi planar scintigraphy were negative, but single photon emission computed tomography/computed tomography (SPECT/CT) demonstrated a tracer-avid retropharyngeal nodule compatible with parathyroid adenoma (PTA). A retrospective review of C
- Maternal depression and its association with responsive feeding and nutritional status of infants: A cross-sectional study from a rural medical college in central IndiaMN Joshi, AV RautJournal of Postgraduate Medicine 2019 65(4):212-218 Context: Globally, around half of all under-5 deaths are attributable to undernutrition. The magnitude of child undernutrition in India is one of the highest in the world. Responsive feeding that has the potential to optimize nutrition and development depends on a “healthy mother”. Objectives: The objective of this study was to find out the magnitude and determinants of matern
- Bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor – A case reportS Karthik, PE Joseph, T BabuJournal of Postgraduate Medicine 2019 65(4):244-246 Dipeptidyl peptidase-4 inhibitors (DPP-4i) are one of the mainstay drugs in the management of type 2 diabetes mellitus. It has been well-documented that these class of drugs cause allergic reactions. Bullous pemphigoid (BP) is a blistering skin condition commonly associated with many drugs. Here, we report a case of probable DPP-4i-induced BP in an elderly man, whic
- Economic burden of slow learners: A prevalence-based cost of illness study of its direct, indirect, and intangible costsS Karande, D Ramadoss, N GogtayJournal of Postgraduate Medicine 2019 65(4):219-226 Aims: The primary objective of this study was to evaluate the economic burden of slow learners (students with “borderline intellectual functioning”) by estimating its direct, indirect, and intangible costs. The secondary objective was to assess the impact of variables on the economic burden. Settings and Design: Cross-sectional, single-arm descriptive study. Sett
- CarotidyniaDA Sanghvi, VB Nakshiwala, TP RautJournal of Postgraduate Medicine 2019 65(4):249-250
- Pharmacovigilance of biosimilars – Why is it different from generics and innovator biologics?B Oza, S Radhakrishna, P Pipalava, V JoseJournal of Postgraduate Medicine 2019 65(4):227-232 Biosimilars are being marketed in India since 2000. Like biologics, biosimilars have a large size, complex structure, and complicated manufacturing process, and they are produced in a living organism. It requires specialized delivery devices for administration and needs tighter temperature control to prevent degradation. As biosimilar development follow
- Endovascular management of persistent sciatic artery occlusionGG Gowda, S Kr, MP TiggaJournal of Postgraduate Medicine 2019 65(4):253-254
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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