- pubmed: frontiers in neurosc...
- Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics.Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics. Front Neurosci. 2019;13:936 Authors: Ramirez-Zamora A, Giordano J, Boyden ES, Gradinaru V, Gunduz A, Starr PA, Sheth SA, McIntyre CC, Fox MD, Vitek J, Vedam-Mai V, Akbar U, Almeida L, Bronte-Stewart HM, Mayberg HS, Pouratian N, Gittis AH, Singer AC, Creed
- Pilot Study of Metabolomic Clusters as State Markers of Major Depression and Outcomes to CBT Treatment.Pilot Study of Metabolomic Clusters as State Markers of Major Depression and Outcomes to CBT Treatment. Front Neurosci. 2019;13:926 Authors: Bhattacharyya S, Dunlop BW, Mahmoudiandehkordi S, Ahmed AT, Louie G, Frye MA, Weinshilboum RM, Krishnan RR, Rush AJ, Mayberg HS, Craighead WE, Kaddurah-Daouk R Abstract Major depressive disorder (MDD) is a common and disabling syndrome with multiple etiologies t
- Linear Registration of Brain MRI Using Knowledge-Based Multiple Intermediator Libraries.Linear Registration of Brain MRI Using Knowledge-Based Multiple Intermediator Libraries. Front Neurosci. 2019;13:909 Authors: Zhang X, Feng Y, Chen W, Li X, Faria AV, Feng Q, Mori S Abstract Linear registration is often the crucial first step for various types of image analysis. Although this is mathematically simple, failure is not uncommon. When investigating the brain by magnetic resonance imaging
- Altered Cingulate Cortex Functional Connectivity in Normal Aging and Mild Cognitive Impairment.Altered Cingulate Cortex Functional Connectivity in Normal Aging and Mild Cognitive Impairment. Front Neurosci. 2019;13:857 Authors: Cera N, Esposito R, Cieri F, Tartaro A Abstract Purpose: Resting-state functional Magnetic Resonance Imaging studies revealed that the brain is organized into specialized networks constituted by regions that show a coherent fluctuation of spontaneous activity. Among the
- Hub Patterns-Based Detection of Dynamic Functional Network Metastates in Resting State: A Test-Retest Analysis.Hub Patterns-Based Detection of Dynamic Functional Network Metastates in Resting State: A Test-Retest Analysis. Front Neurosci. 2019;13:856 Authors: Zhao X, Wu Q, Chen Y, Song X, Ni H, Ming D Abstract The spontaneous dynamic characteristics of resting-state functional networks contain much internal brain physiological or pathological information. The metastate analysis of brain functional networks is
- pubmed: cell cycle arrest
- Cyclin-Like Proteins Tip Regenerative Balance in the Liver to Favour Cancer Formation.Cyclin-Like Proteins Tip Regenerative Balance in the Liver to Favour Cancer Formation. Carcinogenesis. 2019 Oct 02;: Authors: Fifield BA, Talia J, Stoyanovich C, Elliott MJ, Bakht MK, Basilious A, Samsoondar JP, Curtis M, Stringer KF, Porter LA Abstract Hepatocellular carcinoma (HCC) is one of the leading causes of cancer related deaths world-wide. A variety of factors can contribute to the onset of
- ARID5B influences anti-metabolite drug sensitivity and prognosis of acute lymphoblastic leukemia.ARID5B influences anti-metabolite drug sensitivity and prognosis of acute lymphoblastic leukemia. Clin Cancer Res. 2019 Oct 01;: Authors: Yang JJ, Xu H, Zhao X, Bhojwani D, E S, Goodings C, Zhang H, Seibel NL, Yang W, Li C, Carroll WL, Evans WE Abstract PURPOSE: Treatment outcomes for childhood acute lymphoblastic leukemia (ALL) have improved steadily, but a significant proportion of patients still e
- Super-Resolution Microscopy Reveals Local Accumulation of Plasma Membrane Gangliosides at Neisseria meningitidis Invasion Sites.Super-Resolution Microscopy Reveals Local Accumulation of Plasma Membrane Gangliosides at Neisseria meningitidis Invasion Sites. Front Cell Dev Biol. 2019;7:194 Authors: Schlegel J, Peters S, Doose S, Schubert-Unkmeir A, Sauer M Abstract Neisseria meningitidis (meningococcus) is a Gram-negative bacterium responsible for epidemic meningitis and sepsis worldwide. A critical step in the development of m
- Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis.Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis. Front Pharmacol. 2019;10:1029 Authors: Xia Y, Jia C, Xue Q, Jiang J, Xie Y, Wang R, Ran Z, Xu F, Zhang Y, Ye T Abstract Repurposing existing drugs for cancer treatment is an effective strategy. An approved antipsychotic drug, trifluoperazine (TFP), has been reported to have potential anticancer eff
- Diplatin, a Novel and Low-Toxicity Anti-Lung Cancer Platinum Complex, Activation of Cell Death in Tumors via a ROS/JNK/p53-Dependent Pathway, and a Low Rate of Acquired Treatment Resistance.Diplatin, a Novel and Low-Toxicity Anti-Lung Cancer Platinum Complex, Activation of Cell Death in Tumors via a ROS/JNK/p53-Dependent Pathway, and a Low Rate of Acquired Treatment Resistance. Front Pharmacol. 2019;10:982 Authors: Lin X, Jia Y, Dong X, Shen J, Jin Y, Li Y, Wang F, Anenberg E, Zhou J, Zhu J, Chen X, Xie Q, Xie Y Abstract Background: Platinum-based drugs prevail as the main treatment of
- The miR-141/neuropilin-1 axis is associated with the clinicopathology and contributes to the growth and metastasis of pancreatic cancer.The miR-141/neuropilin-1 axis is associated with the clinicopathology and contributes to the growth and metastasis of pancreatic cancer. Cancer Cell Int. 2019;19:248 Authors: Ma L, Zhai B, Zhu H, Li W, Jiang W, Lei L, Zhang S, Qiao H, Jiang X, Sun X Abstract Background: Neuropilin-1 (NRP-1) is a non-tyrosine kinase receptor interacting with multiple signaling pathways that underpin the biological beh
- Ethanol extract of Ligustrum lucidum Ait. leaves suppressed hepatocellular carcinoma in vitro and in vivo.Ethanol extract of Ligustrum lucidum Ait. leaves suppressed hepatocellular carcinoma in vitro and in vivo. Cancer Cell Int. 2019;19:246 Authors: Tian G, Chen J, Luo Y, Yang J, Gao T, Shi J Abstract Background: The present study investigated the pharmacological activity and mechanism of ethanol extract of Ligustrum lucidum Ait. leaves (EEL) on HCC. Methods: Cell viability was determined using
- ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway.ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway. Cancer Manag Res. 2019;11:8547-8555 Authors: Xiao H, Cheng Q, Wu X, Tang Y, Liu J, Li X Abstract Purpose: Acute myeloid leukemia (AML) is the most common type of leukemia and characterized by the malignant growth of leukemic cells. Adenosine deaminases acting on RNA 1 (ADAR1) have been shown
- UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma.UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma. Cancer Manag Res. 2019;11:8359-8370 Authors: Liu LL, Zhu JM, Yu XN, Zhu HR, Shi X, Bilegsaikhan E, Guo HY, Wu J, Shen XZ Abstract Background: Growing evidence suggests that the ubiquitin-proteasome system is involved in the pathogenesis and recurrence of hepatocellular carcinoma (HCC); yet, little is known about the role of
- Inhibition of esophageal cancer growth through the suppression of PI3K/AKT/mTOR signaling pathway.Inhibition of esophageal cancer growth through the suppression of PI3K/AKT/mTOR signaling pathway. Onco Targets Ther. 2019;12:7637-7647 Authors: Shi N, Yu H, Chen T Abstract Background: The phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway is implicated in several cancers. AKT allosteric inhibitor MK2206 and dual PI3K and mTOR inhibitor BEZ235 ar
- A novel CXCL8 analog is effective in inhibiting the growth via cell cycle arrest and attenuating invasion of Lewis lung carcinoma.A novel CXCL8 analog is effective in inhibiting the growth via cell cycle arrest and attenuating invasion of Lewis lung carcinoma. Onco Targets Ther. 2019;12:7611-7621 Authors: Hsu SY, Yu HY, Lee WC, Hsiao CE, Wu CL, Cheng HT, Lin LJ, Li F, Chou YT, Cheng JW Abstract Purpose: Lung cancer and other solid tumors contain not only tumor cells but various types of stromal cells, such as fibroblasts and en
- GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer. Onco Targets Ther. 2019;12:7591-7599 Authors: Han N, Yuan F, Xian P, Liu N, Liu J, Zhang H, Zhang H, Yao K, Yuan G Abstract Background: Bladder cancer (BC) is one of the most prevalent malignancies of the genitourinary system, yet the underlying mechanism of BC progression still remains unclear. Growth arrest and DNA damage
- Up-regulated LncRNA-ATB regulates the growth and metastasis of cholangiocarcinoma via miR-200c signals.Up-regulated LncRNA-ATB regulates the growth and metastasis of cholangiocarcinoma via miR-200c signals. Onco Targets Ther. 2019;12:7561-7571 Authors: Lin H, Yang L, Tian F, Nie S, Zhou H, Liu J, Chen W Abstract Background and objective: Cholangiocarcinoma (CCA) is a highly aggressive neoplasm featured with regional invasiveness and distant metastasis, which often present a phenotype of epithelial-mes
- Tumour-intrinsic resistance to immune checkpoint blockade.Tumour-intrinsic resistance to immune checkpoint blockade. Nat Rev Immunol. 2019 Sep 30;: Authors: Kalbasi A, Ribas A Abstract 'Immune checkpoint blockade' for cancer describes the use of therapeutic antibodies that disrupt negative immune regulatory checkpoints and unleash pre-existing antitumour immune responses. Antibodies targeting the checkpoint molecules cytotoxic T lymphocyte antigen 4 (CTLA4)
- MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt/β-catenin signaling.MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt/β-catenin signaling. Cell Death Dis. 2019 Sep 30;10(10):739 Authors: Gu C, Cai J, Xu Z, Zhou S, Ye L, Yan Q, Zhang Y, Fang Y, Liu Y, Tu C, Wang X, He J, Li Q, Han L, Lin X, Li A, Liu S Abstract The expression panel of plasma microRNA defined miR-532-3p as a valuable biomarker for colorectal adenoma (CRA)
- Protective Role of Fucoidan on Cisplatin-mediated ER Stress in Renal Proximal Tubule Epithelial Cells.Protective Role of Fucoidan on Cisplatin-mediated ER Stress in Renal Proximal Tubule Epithelial Cells. Anticancer Res. 2019 Oct;39(10):5515-5524 Authors: Kim HJ, Yoon YM, Lee JH, Lee SH Abstract BACKGROUND/AIM: Administration of cisplatin in cancer patients is limited by the kidney-related adverse effects; however, a protective strategy is absent. We hypothesized that fucoidan protects the proximal t
- Antitumor Activity of Rivoceranib Against Canine Mammary Gland Tumor Cell Lines.Antitumor Activity of Rivoceranib Against Canine Mammary Gland Tumor Cell Lines. Anticancer Res. 2019 Oct;39(10):5483-5494 Authors: Lee JH, Li Q, An JH, Chae HK, Choi JW, Kim BJ, Song WJ, Youn HY Abstract BACKGROUND/AIM: Canine mammary gland tumors (CMGTs) are the most common tumors in female dogs. Rivoceranib (also known as apatinib) is a novel anti-angiogenic tyrosine kinase inhibitor that selectiv
- Apatinib Reverses Paclitaxel-resistant Lung Cancer Cells (A549) Through Blocking the Function of ABCB1 Transporter.Apatinib Reverses Paclitaxel-resistant Lung Cancer Cells (A549) Through Blocking the Function of ABCB1 Transporter. Anticancer Res. 2019 Oct;39(10):5461-5471 Authors: Zhang Q, Song Y, Cheng X, Xu Z, Matthew OA, Wang J, Sun Z, Zhang X Abstract BACKGROUND/AIM: Multidrug resistance (MDR) is often associated with overexpression of P-glycoprotein (ABCB1) in cancer cells. Apatinib is a novel Vascular endot
- Enhancement of cisplatin-induced cytotoxicity against cervical cancer spheroid cells by targeting long non-coding RNAs.Enhancement of cisplatin-induced cytotoxicity against cervical cancer spheroid cells by targeting long non-coding RNAs. Pathol Res Pract. 2019 Sep 17;:152653 Authors: Li M, Lu B, Dong X, Zhou Y, He Y, Zhang T, Bao L Abstract Cervical cancer (CVC) is one of the most common types of gynecologic malignant tumor in the world. Unfortunately, current treatments including chemo-/radiotherapy still show the
- CDCA7 promotes lung adenocarcinoma proliferation via regulating the cell cycle.CDCA7 promotes lung adenocarcinoma proliferation via regulating the cell cycle. Pathol Res Pract. 2019 Aug 01;:152559 Authors: Wang H, Ye L, Xing Z, Li H, Lv T, Liu H, Zhang F, Song Y Abstract CDCA7 is overexpressed in several malignant cancers and is predicted by bioinformatics to be a candidate oncogene in lung adenocarcinoma (LUAD). However, the clinical and biological function of CDCA7 in LUAD ha
- Estrogen-related receptor β activation and isoform shifting by cdc2-like kinase inhibition restricts migration and intracranial tumor growth in glioblastoma.Estrogen-related receptor β activation and isoform shifting by cdc2-like kinase inhibition restricts migration and intracranial tumor growth in glioblastoma. FASEB J. 2019 Sep 28;:fj201901075R Authors: Tiek DM, Khatib SA, Trepicchio CJ, Heckler MM, Divekar SD, Sarkaria JN, Glasgow E, Riggins RB Abstract Glioblastoma (GBM; grade 4 glioma) is a highly aggressive and incurable tumor. GBM has recently be
- pubmed: future oncology
- Future Oncology; +39 new citations39 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/10/02PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Τετάρτη 2 Οκτωβρίου 2019
- pubmed: frontiers in neurosc...
- pubmed: cell cycle arrest
- pubmed: future oncology
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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00302841026182,
00306932607174,
alsfakia@gmail.com,
Anapafseos 5 Agios Nikolaos 72100 Crete Greece,
Medicine by Alexandros G. Sfakianakis
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