Chronic Respiratory Disease, Volume 16, Issue , January-December 2019. High-flow nasal cannula (HFNC) therapy has been increasingly applied to treat patients with severe hypoxemic respiratory failure. We investigated whether vital signs reflect the reduction of work of breathing in a simulator study and a clinical study. In the simulator study, a standard model high-fidelity human patient simulator (HPS) directly received 35 L/minute of 100% O2 via the HFNC. In the clinical study, the medical records...
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Olubunmi Shoyele, Brent Bacus, Lilliana Haddad, Yilan Li, Vinod ShidhamCytoJournal 2019 16(1):20-20
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Rania Bakkar, James Mirocha, Xuemo Fan, David P Frishberg, Mariza de Peralta-Venturina, Jing Zhai, Shikha BoseCytoJournal 2019 16(1):21-21 Background: The Paris System (TPS) acknowledges the need for more standardized terminology for reporting urine cytopathology results and minimizing the use of equivocal terms. We apply TPS diagnostic terminologies to assess interobserver agreement, compare TPS with the traditional method (TM) of reporting urine cytopathology, and evaluate the rate and positive...
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Abstract Purpose Homogeneous development of temporal bone structures is explained by their ontogenic origin; tegmen tympani (TT) and superior semicircular canal (SSC) are related with the glenoid fossa at the temporomandibular joint (TMJ). Therefore, our objective was to determine a possible relationship between TT status (dehiscence or integrity) and the roof of the glenoid fossa (RGF) thickness; SSC status has also been considered. ...
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Abstract Purpose During right-sided colectomies, surgeons encounter major anatomical variations at the level of the right colon, leading to morbidity. Due to the confusion surrounding the colonic arterial vessels emerging from the superior mesenteric artery (SMA) to vascularize the right part of the colon, this review aimed to describe the arterial vessels found in the mesocolic structures of the ascending colon, the hepatic flexure and...
Mon Oct 21, 2019 03:00
Technology in Cancer Research &Treatment, Volume 18, Issue , January-December 2019. Objective:The aim of this study was to evaluate the relationship between cytokine production, GM-CSF receptor (CSF2RA), and IL-1 receptor (IL1R2) expression in mammary adenocarcinoma and their association with it histopathological parameters and lymph node metastasis.Methods:We analyzed tumor biopsy samples (cultured in vitro) from 50 women (aged 43-75) with invasive ductal mammary adenocarcinomas. Enzyme-linked...
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Technology in Cancer Research &Treatment, Volume 18, Issue , January-December 2019. Using Monte Carlo simulation and a realistic patient model, it is shown that the volume of healthy tissue irradiated at therapeutic doses can be drastically reduced using a combination of standard megavoltage and kilovoltage X-ray beams with a contrast agent previously loaded into the tumor, without the need to reduce standard treatment margins. Four-dimensional computed tomography images of 2 patients with a...
Mon Oct 21, 2019 06:51
Technology in Cancer Research &Treatment, Volume 18, Issue , January-December 2019. Objectives:This study aimed to explore the morphology, loadability, and releasing profiles of CalliSpheres microspheres in delivering oxaliplatin.Methods:Varied amount (20, 40, 60, and 80 mg oxaliplatin) and concentration (1.25, 2.5, 5.0 mg/mL oxaliplatin) of oxaliplatin were mixed with CalliSpheres microspheres with 3 sizes (50-150 μm, 100-300 μm, and 300-500 μm) to measure the loadability. Of all, 20 mg oxaliplatin-loaded...
Mon Oct 21, 2019 06:50
Journal of International Medical Research, Ahead of Print.
Mon Oct 21, 2019 08:43
Journal of International Medical Research, Ahead of Print.
Mon Oct 21, 2019 08:23
Cyclin-dependent kinase regulatory subunit 2 (CKS2) is a member of the cell cycle-dependent protein kinase subunit family, which is implicated as an oncogene in various malignancies. However, the clinical significance, oncogenic functions, and related mechanisms of CKS2 in hepatocellular carcinoma (HCC) remain largely unclear. In the present study, expression features and prognostic value of CKS2 were evaluated in the bioinformatic databases and HCC tissues. The effects of CKS2 on the malignant phenotypes...
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In this study, we evaluated the relationship between circulating betatrophin levels and obesity. Obesity is a common public health problem that is increasing globally. Betatrophin, a newly identified protein, is predominantly expressed in white and brown fat tissues and in the liver. Growing evidence suggests that betatrophin plays a pivotal role in metabolism, including the synthesis and degradation of lipids in cells, and adipocyte differentiation. Previous studies have assessed the association...
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Objective. To determine the expression levels of KIF18A in lung adenocarcinoma and its relationship with the clinicopathologic features of patients undergoing radical colectomy and explore the potential role in the progression of lung adenocarcinoma. Methods. Immunohistochemical assays were performed to explore the expression levels of KIF18A in 82 samples of lung adenocarcinoma and corresponding normal tissues. According to the levels of KIF18A expression in lung adenocarcinoma tissue samples, patients...
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Background and Objective. Liver cancer is a common malignant tumor with few poor diagnostic and prognostic markers, which greatly shortens the potential life span of patients. The RNA-binding protein la ribonucleoprotein 4B (LARP4B) has a la motif (lam) that is important in the process of cancer. We aimed to explore the role of LARP4B in the diagnosis and prognosis of liver cancer. Methods. The Cancer Genome Atlas (TCGA) database was searched to detect LARP4B gene expression in liver cancer. The...
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Pediatric Allergy, Immunology, and Pulmonology, Ahead of Print.
Mon Oct 21, 2019 10:00
Abstract This work proposed the diagnosis of iron deficiency anemia (IDA) and sickle cell disease (SCD) in human blood caused by iron deficiency and hemoglobin S (HbS), which are among the most common anemias, by means of Raman spectroscopy. Whole blood samples from patients diagnosed with IDA and HbS, as well as from normal subjects (HbA), were obtained and submitted to Raman spectroscopy (830 nm, 150 mW, 400–1800 cm−1 spectral range, 4 cm−1 resolution). Difference spectra of...
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Rejuvenation Research, Volume 22, Issue 5, Page 439-446, October 2019.
Thu Oct 17, 2019 10:00
Rejuvenation Research, Volume 22, Issue 5, Page 375-376, October 2019.
Thu Oct 17, 2019 10:00
Abstract Azaphilones are a class of fungal pigments, reported mostly in association with Monascus species. In Asian countries, they are used as food colourants under the name of “red yeast rice” and their production process is well described. One major limitation of current production techniques of azaphilones is that they always occur in a mixture of yellow, orange and red pigments. These mixtures are difficult to control and to quantify. This study has established a controlled...
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Abstract This work aimed at investigating the chemical composition, antibacterial properties, and effect mechanism of Smilax china L. polyphenols (SCLP). SCLP was extracted and purified, and then, its eighteen polyphenolic compounds were identified by LC-MS/MS analysis. SCLP exhibited antibacterial activity against five bacteria (Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bacillus subtilis, and Escherichia coli) with minimum inhibitory concentration...
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Abstract D-Mannose is an epimer of glucose at the C-2 position and exists in nature as a component of mannan. It has 60 and 86% sweetness than that of sucrose and D-glucose, respectively. Because of its low-calorie and nontoxic features, D-mannose is used widely in food, medicine, cosmetic, and food-additive industries. Besides, it exhibits many physiologic benefits on health: immune system, diabetes mellitus, intestinal diseases, and urinary tract infections. It is used as a starting...
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Abstract Insulin therapy remains the most effective method to treat diabetes mellitus (DM), and the demand for this valuable hormone has exceeded that of any other protein-based medicine as a result of the dramatic increase in the number of diabetic patients worldwide. Understanding the structure of insulin and the interaction with its receptor is important for developing proper formulations. As a result of the relatively low thermal stability of native insulin and its two-chain...
Mon Oct 21, 2019 03:00
Abstract Microbial-induced CaCO3 precipitation has been widely applied in bacterial-based self-healing concrete. However, the limited biogenetic CaCO3 production by bacteria after they were introduced into the incompatible concrete matrix is a major challenge of this technology. In the present study, the potential of combining two metabolic pathways, urea hydrolysis and nitrate reduction, simultaneously in one bacteria strain for improving the bacterial CaCO3 yield has been investigated....
Mon Oct 21, 2019 03:00
Journal of Neurotrauma, Ahead of Print.
Mon Oct 21, 2019 10:00
Journal of Neurotrauma, Ahead of Print.
Mon Oct 21, 2019 10:00
Journal of Neurotrauma, Ahead of Print.
Fri Oct 18, 2019 10:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01591D, PaperEunjin Jang, Tung Duy Vu, Dongho Choi, Yun Kyung Jung, Kyeong Geun Lee, Hoeil ChungA whole-sample-covering near-infrared (NIR) spectroscopic scheme has been adopted for simple drop-and-dry measurement of raw bile juice for identification of gallbladder (GB) diseases of stone, polyp, and cancer. For reproducible...The content of this RSS Feed (c) The Royal Society of Chemistry
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Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01946D, PaperXiaomeng Liu, Taotao Feng, Wenliang Ji, Zhaojun Wang, Meining ZhangIt is of interest to in vivo monitor the co-dynamics of different substances. However, the tracking of multiple species is still challenging. In this work, we demonstrate an in vivo...The content of this RSS Feed (c) The Royal Society of Chemistry
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Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01697J, CommunicationSunho Kim, Ho Sang Jung, Dong-Ho Kim, Shin-Hyun Kim, Sung-Gyu ParkThe detection of toxic gas molecules using the surface-enhanced Raman spectroscopy (SERS) technique is very challenging due to low affinity of gas molecules. Here, we report on extremely sensitive SERS-based...The content of this RSS Feed (c) The Royal Society of Chemistry
Mon Oct 21, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01769K, CommunicationYusuke Niwa, Tatsumi Mizuta, Kenji Sueyoshi, Tatsuro Endo, Hideaki HisamotoA highly lipophilic ionic liquid (IL) consisting of stoichiometrically equal amounts of two purely functional chemical sensing molecules, an anionic calcium ionophore and a cationic dye, was synthesized for the...The content of this RSS Feed (c) The Royal Society of Chemistry
Mon Oct 21, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01653H, PaperYu Zhou, Huiying Xu, Hua Wang, Bang-Ce YeExosomes are membrane-enclosed phospholipid extracellular vesicles with a variety of tumor antigens which can be applied in the diagnosis and treatment of cancer due to the high secretion on the...The content of this RSS Feed (c) The Royal Society of Chemistry
Mon Oct 21, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01140D, PaperJunwoo Lee, Hye Rin Kim, Youhee Hur, Yong Kyoung Yoo, Sung Il Han, Cheonjung Kim, Don Hur, Hyungseok Kim, Ji Yoon Kang, Jeonghoon LeeEVs/exosomes are considered as the next generation of biomarkers, including for liquid biopsies. Consequently, the quantification of EVs/exosomes is crucial in facilitating EVs/exosomes research and applications. Paper-based enzyme-linked immunosorbent assay...The content of this RSS Feed (c) The Royal Society...
Mon Oct 21, 2019 02:00
Tissue Engineering Part A, Ahead of Print.
Fri Oct 18, 2019 10:00
Abstract Rationale Animal studies have found robust sex differences in the pharmacokinetics and pharmacodynamics of Δ9-tetrahydrocannabinol (THC). However, the human evidence remains equivocal, despite findings that women may experience more severe consequences of cannabis use than men. Objectives The objective of this secondary analysis was to examine sex...
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The physiognomical masks of Lorenzo Tenchini at the University of Parma in the 19th century can be considered the first historical antecedent of the experimental method for transferring a strip of face from a deceased donor to a living recipient, in preparation for a face transplant. They are a relevant example of mixed ceroplastic‐cutaneous preparations, and were fabricated with a procedure conceptually mimicking the modern additive layer manufacturing for 3D printing of anatomical structures. Abstract...
Mon Oct 21, 2019 16:47
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