• 
  Vocal and Laryngeal Symptoms and Associated Factors in Wind Instrumentalists: A Systematic Review

  This is a systematic literature review to identify vocal and laryngeal symptoms and associated factors in adult wind instrumentalists.

  Journal of Voice

  Sun Oct 13, 2019 17:00
• Medgadget
• Noble’s Self-Injection Trainers for Rheumatoid Arthritis Drugs: Interview with Joe Reynolds, Research Manager

  Last year, Medgadget heard from Noble International about its “smart” training devices that educate patients on safe and effective at-home use of prefilled syringes and autoinjectors. At the time, Joe Reynolds, Research Manager at Noble International, shared some use cases for the company’s products, including rheumatoid arthritis (RA). Since that interview, longitudinal data has proven the efficacy of Noble’s training devices in clinical

  Medgadget

  Mon Oct 14, 2019 08:30
• Microfluidic Device for Rapid Lyme Disease Diagnosis

  Researchers at Columbia University have developed a microfluidic device that can diagnose Lyme disease in as little as 15 minutes. The device is particularly accurate in identifying antibody biomarkers that are present during early stage Lyme disease, raising hopes that it could be useful in detecting cases of early infection in a doctor’s office, leading to timely treatment. Lyme disease, which is spread by infected ticks, is incredibly

  Medgadget

  Mon Oct 14, 2019 06:17
• Angewandte Chemie International Edition
• Enantioselective control of both helical and axial stereogenic elements via an organocatalytic approach

  Abstract: A highly diastereo‐ and enantio‐selective method for the asymmetric synthesis of molecules containing helicenes and stereogenic axes was developed based on organocatalysis. Various compounds bearing both helical and axial stereogenic elements were obtained in excellent enantioselectivities. The mechanism study revealed that the reaction proceeded through two stages: 1) The first cyclization produces a reaction intermediate containing a

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 08:02
• Xenon Recovery by DD3R Zeolite Membranes: Application in Anaesthetics

  Hydrophobic DD3R zeolite is a benchmark membrane material for Xe recovery. The CO2 permeance is one order magnitude higher than conventional membranes and is less susceptible to humidity. The high performance and long‐term stability endow DD3R zeolite membranes great potential for on‐stream CO2 removal from the exhaled Xe‐based anaesthetic gas. Abstract Xe is only produced by cryogenic distillation of air, and its availability is limited by

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 08:02
• Facile C=O Bond Splitting of Carbon Dioxide Induced by Metal–Ligand Cooperativity in a Phosphinine Iron(0) Complex

  CO2 splitting by a single iron centre is achieved through the joint action of the metal atom and the 2‐(2′‐pyridyl)‐4,6‐diphenylphosphinine ligand (L) in the ferrate anion [Cp*FeL]− (Cp*=C5Me5). The outcome of the reaction depends on the coordination mode of L. Electrophilic addition of CO2 to the phosphinine group is observed when L is π‐coordinated, while the σ‐coordinated ligand induces C=O bond cleavage. Abstract New iron complexes [Cp*

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 06:07
• Late‐Stage Functionalization of Histidine in Unprotected Peptides

  The late‐stage functionalization (LSF) of peptides represents a valuable strategy for the design of potent peptide pharmaceuticals by enabling rapid exploration of chemical diversity and offering novel opportunities for peptide conjugation. While the C(sp 2 )−H activation of tryptophan (Trp) is well documented, the resurgence of radical chemistry is opening new avenues for the C−H functionalization of other aromatic side‐chains. Herein, we repo

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 06:05
• Base‐Stabilized [PO]+/[PO2]+ Cations

  The salts [(BAC) 2 PO][BF 4 ] ( 5 ) and [(BAC) 2 PO 2 ][BF 4 ] ( 4 ) (BAC = bis(diisopropylamino) cyclopropenylidene), consisting of the PO + and PO 2 + cations, respectively, coordinated to the singlet carbenes, have been prepared. Computational investigations reveal that the electronic structure of the PO + cation is a hybrid between the charge‐localized and charge‐delocalized resonance forms resulting in ambiphilic reactiv

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 06:00
• Hypergolic Triggers as Cocrystal Formers: Cocrystallization for Creating New Hypergolic Materials with Tunable Energy Content

  We demonstrate a cocrystal‐based strategy to create new solid hypergols, i.e. materials exhibiting spontaneous ignition in contact with an oxidant, from typically non‐hypergolic fuel molecules, in which the energy content and density of the material can be changed without affecting the ignition delay. Using an imidazole‐substituted decaborane as a hypergolic “trigger” component, in combination with energy‐rich but non‐hypergolic nitrobenzene or p

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 05:54
• Anisotropically Electrochemo‐Mechanical Evolution in Solid‐State Batteries and Interfacial Tailored Strategy

  All‐solid‐state batteries have attracted extensive attention owing to the potential high energy density and safety; however, little success has been made on the practical application solid‐state batteries, which is largely attributed to the solid‐solid interfacial issues. A fundamental elucidation of electrode‐electrolyte interface behaviors is of crucial significance but has proven difficult. Here we probed the interfacial resistance and capacit

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 05:38
• Additions to N‐Sulfinylamines as an Approach for the Metal‐free Synthesis of Sulfonimidamides: O‐Benzotriazolyl Sulfonimidates as Activated Intermediates

  Sulfonimidamides are obtained in moderate to very good yield from O‐benzotriazolyl sulfonimidates, which are key intermediates formed by reacting aryldiazonium tetrafluoroborates, N‐tritylsulfinylamine, and N‐hydroxybenzotriazole hydrate, mediated by a tertiary amine. The latter transformation proceeds in inexpensive and environmentally benign dimethyl carbonate as solvent, it does not require anhydrous conditions, and the product yields are gene

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 05:34
• Site‐specific encoding of photoactivity in antibodies enables light‐mediated antibody‐antigen binding on live cells

  Antibodies have found applications in several fields, including, medicine, diagnostics, and nanotechnology, yet methods to modulate antibody‐antigen binding using an external agent remain limited. Here, we have developed photoactive antibody fragments by genetic site‐specific replacement of single tyrosine residues with photocaged tyrosine, in an antibody fragment, 7D12. A simple and robust assay is adopted to evaluate the light‐mediated binding

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 05:14
• Palladium single atoms on TiO2 as a photocatalytic sensing platform for analyzing organophosphorus pesticide chlorpyrifos

  Traditional methods for analyzing organophosphorus pesticide chlorpyrifos, usually require the tedious sample pretreatment and sophisticated bio‐interfaces, inevitably leading to the difficulty for real‐time analysis. Herein, we first adopt palladium single‐atom (PdSA)/TiO 2 as an advanced photocatalytic sensing platform for directly detecting the chlorpyrifos with high sensitivity and selectivity through restricting the photocatalytic H 2 ev

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 05:09
• Theranostic Nanoplatform with Hydrogen Sulfide Activatable NIR Responsiveness for Imaging‐Guided On‐Demand Drug Release

  Drug release: A theranostic nanoplatform for precision cancer medicine was developed. This platform features H2S‐activatable NIR responsiveness for photocontrolled on‐demand drug release in vivo. The platform enables effective tumor suppression because of the synergistic cancer‐specific and NIR light activated processes. Abstract NIR light responsive nanoplatforms hold great promise for on‐demand drug release in precision cancer medicine. H

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 04:35
• Enzymatic Incorporation of a Coumarin‐Guanine Base Pair

  Replacements: A single C−H can replace N−H at a Watson–Crick‐type interface with preservation of functional selectivity and enhanced activity. As demonstrated here, dGTP is selectively incorporated across from the new, highly fluorescent deoxycytidine mimic 3‐gylcosyl‐5‐fluoro‐7‐methoxy‐coumarin‐2′‐deoxyribose (dC C ) during enzymatic DNA synthesis. Likewise, dC C TP is selectively incorporated across from a guanine

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 04:30
• Significant upregulation of Alzheimer's β‐amyloid levels in living system induced by extracellular elastin polypeptides

  Alzheimer’s disease (AD) is a neurodegenerative disorder and the primary cause of age‐related dementia. The etiology of AD is complex and has not been completely elucidated. Here, we investigated whether the components from brain extracellular matrix (ECM), particularly the fibrous entities, may influence the pathogenesis of AD. We showed that elastin‐like polypeptides (ELPs), ECM‐related molecules with low complexity significantly increased the

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 04:23
• Regioselective Hydrosilylation of Olefins Catalyzed by a Molecular Calcium Hydride Cation

  Chemo‐ and regioselectivity are often difficult to control during olefin hydrosilylation catalyzed by d‐ and f‐block metal complexes. The cationic hydride of calcium [CaH]+ stabilized by an NNNN macrocycle was found to catalyze the regioselective hydrosilylation of aliphatic olefins to give anti‐Markovnikov products, while aryl substituted olefins were hydrosilyated with Markovnikov regioselectivity. Ethylene was efficiently hydrosilylated by pri

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 02:54
• Symmetric, unsymmetric and asymmetric [13]helicenes

  Fully aromatic helicenes with more than one pitch‐length are illustrious synthetic targets with potential applications in advanced optical devices and nano‐electronics. The task of extending the length of fully conjugated helicenes past one pitch‐length has proven challenging. We herein describe our synthesis of a series of azaoxa[7]‐, [10]‐ and [13]helicenes. Their synthesis is based on iterative oxidative furan formation between 3,6‐dihydroxyca

  Angewandte Chemie International Edition

  Mon Oct 14, 2019 02:24
• Enhanced Lifetime and Photostability with Low‐temperature Mesoporous ZnTiO3/Compact SnO2 Electrodes in Perovskite Solar Cells

  Perovskite solar cells (PSC) which have exceeded power conversion efficiencies (PCEs) of 25% are mainly demonstrated by using SnO 2 or TiO 2 as electron‐transporting layers (ETLs). However, high‐performance planar PSCs need precise process, which is difficult for large‐scale production. Mesoporous structure shows better operability but with high‐temperature process. Besides, as the most used mesoporous materials, the strong photocatalytic eff

  Angewandte Chemie International Edition

  Sun Oct 13, 2019 11:53
• Strain‐induced isomerization in one‐dimensional metal‐organic chains

  The ability to use mechanical strain to steer chemical reactions creates completely new opportunities for solution‐ and solid‐phase synthesis of functional molecules and materials. However, this strategy is not readily applied in the bottom‐up on‐surface synthesis of well‐defined nanostructures. Here, we report an internal strain‐induced skeletal rearrangement of one‐dimensional (1D) metal‐organic chains (MOCs) via a concurrent atom shift and bon

  Angewandte Chemie International Edition

  Sun Oct 13, 2019 11:23
• Total Synthesis of (–)‐Perezoperezone through an Intermolecular [5+2] Homodimerization of Hydroxy p‐Quinone

  The first copper‐catalyzed intermolecular [5+2] homodimerization of hydroxy  p ‐quinone is presented, furnishing bicyclo[3.2.1]octadienone core structures in typically good yields and excellent diastereoselectivities. Applying this synthetic approach enables a concise nine‐step total synthesis of (–)‐perezoperezone from commercially available 3, 5‐dimethoxytoluene.

  Angewandte Chemie International Edition

  Sun Oct 13, 2019 07:00
• NeuroImage
• Anterior fissure, central canal, posterior septum and more: New insights into the cervical spinal cord gray and white matter regional organization using T₁ mapping at 7T

  Publication date: Available online 13 October 2019Source: NeuroImageAuthor(s): Aurélien Massire, Henitsoa Rasoanandrianina, Maxime Guye, Virginie CallotAbstractT1 mapping lacks specificity toward a single particular biological feature, however it has the potential to discriminate spinal cord regional tissue organization and characterize tissue microstructural impairments occurring in neurodegenerative pathologies. In this exploratory work, T1 map

  NeuroImage

  Mon Oct 14, 2019 07:17
• Radiation Oncology - Latest Articles
• Conventional versus hypofractionated postmastectomy radiotherapy: a report on long-term outcomes and late toxicity

  We evaluated the long-term outcomes and late toxicity of conventional fractionated (CF) and hypofractionated (HF) postmastectomy radiotherapy (PMRT) in terms of locoregional recurrence-free survival (LRRFS), d...

  Radiation Oncology - Latest Articles

  Sun Oct 13, 2019 17:00
• Cortex
• Electrophysiological evidence of phonemotopic representations of vowels in the primary and secondary auditory cortex

  Publication date: Available online 13 October 2019Source: CortexAuthor(s): Anna Dora Manca, Francesco Di Russo, Francesco Sigona, Mirko GrimaldiAbstractHow the brain encodes the speech acoustic signal into phonological representations is a fundamental question for the neurobiology of language. Determining whether this process is characterized by tonotopic maps in primary or secondary auditory areas, with bilateral or leftward activity, remains a

  Cortex

  Mon Oct 14, 2019 06:27
• Analytical Chemistry
• [ASAP] Retention Time Prediction for Glycopeptides in Reversed-Phase Chromatography for Glycoproteomic Applications

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b02584

  Analytical Chemistry

  Sun Oct 13, 2019 21:00
• [ASAP] Easy-to-Use Sensors for Field Monitoring of Copper Contamination in Water and Pesticide-Sprayed Plants

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b03385

  Analytical Chemistry

  Sun Oct 13, 2019 21:00
• [ASAP] Consecutive Sorting and Phenotypic Counting of CTCs by an Optofluidic Flow Cytometer

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b04035

  Analytical Chemistry

  Sun Oct 13, 2019 21:00
• [ASAP] Introducing Frontal Chromatography–Inductively Coupled Plasma-Mass Spectrometry as a Fast Method for Speciation Analysis: The Case of Inorganic Arsenic

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b03279

  Analytical Chemistry

  Sun Oct 13, 2019 21:00
• [ASAP] Comprehensive Monosaccharide Composition Analysis of Insoluble Polysaccharides by Permethylation To Produce Methyl Alditol Derivatives for Gas Chromatography/Mass Spectrometry

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b03239

  Analytical Chemistry

  Sun Oct 13, 2019 21:00
• [ASAP] Pacifier Biosensor: Toward Noninvasive Saliva Biomarker Monitoring

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b03379

  Analytical Chemistry

  Sun Oct 13, 2019 21:00
• Experimental Dermatology
• Why is hair curly? ‐ Deductions from the structure and the biomechanics of the mature hair shaft

  Abstract The final shape of a head hair is predetermined through a variety of factors during its formation in the follicle. These are genetic pathways, specific growth factors, cell differentiation and segregation, etc., with spatial as well as chronological dynamics. The cortex of hair consists of two major cell groups. These are characterized by parallel (para‐type) or roughly helical arrangement (ortho‐type) of the intermediate filaments (IF)

  Experimental Dermatology

  Mon Oct 14, 2019 04:46
• British Association of Plastic Surgeons
• Body mass index and Abdominal wall thickness correlate with perforator caliber in free abdominal tissue transfer for Breast Reconstruction

  Publication date: Available online 14 October 2019Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Maxi Sacher, Roman N. Kapalschinski, Christoph Wallner, Johannes Maximilian Wagner, Mehran Dadras, Tobias Hirsch, Christoph Heute, Volkmar Nicolas, Marcus Lehnhardt, Björn BehrAbstractIntroductionThe aim of the study was to investigate the relationship between the BMI and abdominal wall thickness (AWT) as opposed to diameter

  British Association of Plastic Surgeons

  Mon Oct 14, 2019 06:19
• Clinical Oral Implants Research
• Accuracy of digital impressions for implant‐supported complete‐arch prosthesis, using an auxiliary geometry part – an in vitro study

  Abstract Objectives The aim of this study was to evaluate the accuracy of complete‐arch digital impressions for fabrication of an implant‐supported prosthesis in the edentulous maxilla using an auxiliary geometry part. Material and Methods A replica of the upper jaw of an edentulous patient with four scannable impression copings was fabricated in stainless steel. This model was scanned with an industrial non‐contact 3D structured blue l

  Clinical Oral Implants Research

  Mon Oct 14, 2019 12:04
• Effects of different types of intraoral scanners and scanning ranges on the precision of digital implant impressions in edentulous maxilla: An in vitro study

  Abstract Objective This study aimed to evaluate the precision of digital implant impressions in comparison with conventional impressions and assess the impact of the scanning range on precision. Materials and Methods An edentulous maxilla model with six implants was scanned with four intraoral scanners (IOSs) and a dental laboratory scanner five times each, and stereolithography (STL) data were generated. A conventional silicone impress

  Clinical Oral Implants Research

  Sun Oct 13, 2019 11:29
• Dental implants placed in atrophic jaws reconstructed with autogenous mandibular bone blocks covered by bovine bone mineral and collagen membranes – A 3‐ to 16‐year follow‐up study

  Clinical Oral Implants Research

  Wed Sep 25, 2019 12:00
• Journal of Prosthodontics
• Retrieval of Glass Fiber Post using Er:YAG Laser and Conventional Endodontic Ultrasonic Method: An In Vitro Study

  Abstract Purpose To compare the times and temperatures used to remove a glass fiber post from an endodontically‐treated tooth using erbium‐doped yttrium aluminum garnet (Er:YAG) compared to conventional endodontic ultrasonic method. Materials and Methods Thirty four single‐root human extracted teeth were endodontically treated ex vivo. The post space was prepared to 7 mm in depth and a 11.4 mm glass fiber post was cemented using composi

  Journal of Prosthodontics

  Mon Oct 14, 2019 12:13
• European Journal of Neuroscience
• Pavlovian‐to‐instrumental‐transfer in Anorexia Nervosa: A pilot‐study on conditioned learning and instrumental responding to low‐ and high‐calorie food stimuli

  Abstract Anorexia Nervosa is characterized by persistent restraint eating despite severe negative consequences and often a chronic course of the disease. Recent theoretical models suggest that abnormalities in reward‐processing and incentive salience of disorder‐compatible stimuli as observed in addictive behaviors contribute to the development and maintenance of Anorexia Nervosa. The aim of the present study was to investigate the process of th

  European Journal of Neuroscience

  Sun Oct 13, 2019 03:23
• Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)
• Ambient Electrospray Deposition Raman Spectroscopy (AESD RS) using Soft Landed Preformed Silver Nanoparticles for Rapid and Sensitive Analysis

  Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01700C, PaperTripti Ahuja, Atanu Ghosh, Sandip Mondal, Pallab Basuri, Jenifer Shantha Kumar, Pillalamarri Srikrishnarka, Jyoti Sarita Mohanty, Sandeep Bose, T. PradeepWe introduce a technique called ambient electrospray deposition Raman spectroscopy (AESD RS) for rapid and sensitive surface-enhanced Raman scattering (SERS) based detection of analytes using a miniature Raman spectrometer. Using..

  Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

  Mon Oct 14, 2019 16:00
• The electrochemical application of rare earth based nanomaterials

  Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01562K, MinireviewHaiping Huang, Jun-Jie ZhuAs a series of important metal materials, rare earth elements and their relative derivative compounds have received considerable attention because of their narrow emission bands, noncytotoxicity, excitation of multiple fluorescence...The content of this RSS Feed (c) The Royal Society of Chemistry

  Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

  Sun Oct 13, 2019 16:00
• One-pot green and simple synthesis of actinian nickel-doped carbon nanoflowers for ultrasensitive sensing of quercetin

  Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01907C, PaperYuan-Fei Gao, Xing Jin, Fen-Ying Kong, Zhong-Xia Wang, Wei WangIn this contribution, a one-pot method possessing the advantages of easily prepared, rapid, efficient and environmentally friendly, has been developed for facile synthesis of highly fluorescent actinian nickel-doped carbon nanoflowers...The content of this RSS Feed (c) The Royal Society of Chemistry

  Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

  Sun Oct 13, 2019 16:00
• Fingerprint of Amyloid Plaque in a Bitransgenic Animal Model of Alzheimer Disease Obtained by Statistical Unmixing Analysis of Hyperspectral Raman Data

  Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01631G, PaperEmerson A Fonseca, Lucas Lafetá, Renan Cunha, Hudson Miranda, João Campos, Helton Medeiros, Marco Aurelio Romano-Silva, Raigna Silva, Alexandre Barbosa, Rafael Vieira, L Malard, Ado JorioGlobal prevalence of Alzheimer’s disease (AD) points to endemic levels, especially considering the increase on average life expectancy worldwide. AD diagnosis based on early biomarkers, in addition t

  Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

  Sun Oct 13, 2019 16:00
• Structure characterization and optical properties investigation of four main components in classical phenazinium dye Safranin O

  Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01410A, CommunicationHong Wan, Hong Chen, Yueying Chu, Xiu-Lian Ju, Haipeng JiangSafranin O is an important and classical phenazinium dye since the 19th century, it has been extensively used in academic field as spectroscopic probe and indicator. Surprisingly, we found that...The content of this RSS Feed (c) The Royal Society of Chemistry

  Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

  Sun Oct 13, 2019 16:00