Abstract The present study evaluated the effects of low doses of atrazine administered during gestation and breastfeeding on sperm characteristics of the wild rodent Calomys laucha. Adult females were divided into groups of 10 and administered different doses of atrazine through gavage, during gestational or breastfeeding period. At 3 months of age, the F1 adult male progeny of these females was evaluated. We observed a drastic reduction in the total and progressive motility of...
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Although most U.S. physicians train at Veterans Health Administration hospitals, few have served in the military. The author, a veteran and physician, discusses how failure to appreciate the differences between civilian and military cultures can result in veterans' and physicians' perspectives being misaligned when managing a veteran's health.
Evidence suggests that cognitive behavioral therapy and second-generation antidepressants are equally effective in treating major depressive disorder. Ross and colleagues examine the cost-effectiveness of these therapies. The editorialist discusses why these findings support the need to assure the availability of both therapeutic options.
Academic medical institutions have recognized the need to improve diversity among faculty members, trainees, and students. Persons from underrepresented minority (URM) groups are often asked to serve on search committees to help with these efforts. This article suggests that this places undue burden on URM persons while unintentionally lessening the responsibility among those in the majority for helping to improve diversity in academic medical institutions.
Background:Most guidelines for major depressive disorder recommend initial treatment with either a second-generation antidepressant (SGA) or cognitive behavioral therapy (CBT). Although most trials suggest that these treatments have similar efficacy, their health economic implications are uncertain.Objective:To quantify the cost-effectiveness of CBT versus SGA for initial treatment of depression.Design:Decision analytic model.Data Sources:Relative effectiveness data from a meta-analysis of randomized...
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Abstract The establishment of fragmentation pathways has a great interest in the identification of new or unknown related compounds present in complex samples. On that way, tentative fragmentation pathways for the ions generated by atmospheric pressure ionization of neutral per- and polyfluorinated alkyl substances (PFASs) have been proposed in this work. Electrospray (ESI), atmospheric pressure chemical ionization (APCI) and photoionization (APPI) were evaluated using mobile phases...
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Topical anesthetic creams are widely used to provide local anesthesia in dermatologic surgery. To achieve the desired effect, a certain degree of penetration is required. This effect can be achieved by occlusion with a transparent dressing. However, the use of dressings for occlusion can lead to spillage of the cream, which can result in a poor anesthetic effect.1 The recommended dose of the drug is 1.5-2 g per 10 cm2 area of skin, which might not be retained under the occlusive dressing.2 Furthermore,...
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There are many possible causes of a swollen toe. In this article, find out about the different causes and their associated symptoms and treatments.
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ObjectivesTo systematically review the efficacy and safety of anti-inflammatory agents for patients with major depressive disorders.MethodsWe searched the literature to identify potentially relevant randomised controlled trials (RCTs) up to 1 January 2019. The primary outcome was efficacy, measured by mean changes in depression score from baseline to endpoint. Secondary outcomes included response and remission rates and quality of life (QoL). Safety was evaluated by incidence of classified adverse...
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Kyocera of Japan has just unveiled the first carbohydrate metabolism measurement device. The system is portable and users can assess their carbohydrate metabolism just about anywhere. The soon to be released product is a radial arterial pulse wave gyro sensor that analyzes pulse-wave patterns at the wrist. Kyocera hopes that this new device will help with dietary monitoring and help users to manage conditions such as diabetes and pre-diabetes. The user simply places the sensor against the...
Manipulating individual cells and microscopic particles may be extremely valuable for testing new therapies, targeting tumors, and for studying the underlying causes of disease, but it is very difficult to directly manipulate individual cells within an environment shared with other cells. A collaboration of researchers from University of California San Diego, University of Pennsylvania, and Harbin Institute of Technology in China has developed pretty amazing microscopic devices that can move...
Earlier this year, Medgadget reported on the FDA’s clearance of the SEM Scanner, a device created by Los Angeles-based Bruin Biometrics (BBI). The SEM Scanner is a wireless, handheld device that detects changes in sub-epidermal moisture as an indicator of risk for developing a pressure ulcer. Moisture can indicate the presence of localized edema and tissue fluid-related inflammation well before visual and tactile tests that represent the diagnostic standard of care today. To learn more about the...
Electrospinning is a manufacturing technique that has recently been getting a lot of attention in medicine because it allows researchers to produce novel materials and devices. Essentially, a polymer is melted and squeezed through a nozzle and an electric field is used to pull and spin it into a mesh of very fine fiber. The material has a huge surface area, given its volume, and it can be combined with drugs and other devices, and used as a part of therapies in all sorts of ways. There’s also...
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Radiologic evidence of successful lumbar fusion has traditionally been based on bridging bone spanning the intertransverse processes (posterolateral fusion or PLF) or disc space (interbody fusion, or IBF). Often, postoperative computed tomography (CT) of unsuccessful PLF and IBF demonstrates bridging bone across the facet joints or connecting the medial transverse process to the ipsilateral superior articular facet of the caudal vertebra. The significance of this finding in terms of implant stability...
Multisensory afferent inputs to the cervical spine affect the generation of neck muscle control. Chronic neck pain (CNP) and muscle fatigue are factors that disturb somatosensory function. Whether they affect postural control under self-initiated perturbation in daily activities is still unclear.
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Overall survival was improved versus chemotherapy in non–small-cell lung cancer patients, independent of their PD-L1 status or tumor mutational burden.
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Papillary squamotransitional cell carcinoma of the uterine cervix is a rare neoplasm, a subtype of transitional cervical carcinoma that appears to be a variation of squamous cervical carcinoma. It has a dispos...
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43 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Asian Pac J Cancer Prev"[jour] These pubmed results were generated on 2019/10/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Audience: Consumer, Health Professional, Pharmacy October 26, 2019 -- Mylan Pharmaceuticals Inc. is conducting a voluntary nationwide recall of one lot (see table below) of Alprazolam Tablets, USP C-IV 0.5 mg, to the consumer/user level. This lot is...
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Related ArticlesIdiopathic Nonhistaminergic Acquired Angioedema Versus Hereditary Angioedema. J Allergy Clin Immunol Pract. 2018 Jul - Aug;6(4):1205-1208 Authors: Andrási N, Veszeli N, Kőhalmi KV, Csuka D, Temesszentandrási G, Varga L, Farkas H Abstract BACKGROUND: The mechanism of idiopathic nonhistaminergic acquired angioedema (InH-AAE) has not yet been precisely elucidated. This condition is characterized by recurrent angioedema without wheals. ...
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Related Articles[Diagnostic value of digital breast tomosynthesis for mass lesions in dense breast]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3110-3113 Authors: Lü XJ, Liu N, Li Q, Li M, Zhang XL Abstract Objective: To explore the diagnostic efficiency of digital breast tomosynthesis (DBT) for mass lesions in dense breast by comparing with digital mammography (DM). Methods: A retrospective analysis was made of 125 female patients with breast masses...
Related Articles[The value of DCE-MRI in predicting IDH gene mutation of high-grade gliomas]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3105-3109 Authors: Lu HT, Xing W, Zhang YW, Qin HP, Wu RH, Ding JL Abstract Objective: To investigate the value of quantitative and semiquantitative parameters of DCE-MRI in predicting IDH gene mutation of high-grade gliomas before the operation. Methods: Twenty-six individuals with surgically and pathologically proved...
Related Articles[Efficacy and safety of compound betamethasone cocktail therapy in primary unilateral unicompartmental knee arthroplasty]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3100-3104 Authors: Liu P, Guo WS, Zhang QD, Wang WG, Zhang Y, Wang YY Abstract Objective: To evaluate the efficacy and safety of an intraoperative betamethasone periarticular injection in patients undergoing primary unicompartmental knee arthroplasty (UKA). Methods: Seventy...
Related Articles[Adult femur CT modeling and 3D automatic measurement of anatomical parameters]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3093-3099 Authors: Xue L, Li Q, Hu GF, Shen L, Li LB, Jin ZG, Zhu ZL, Xie ZG Abstract Objective: To reconstruct a 3D model from adult femur CT scan data and automate a measurement of femoral anatomical parameters to study the characteristics of Chinese femur anatomical parameters. Methods: Using Mimics17.0, models...
Related Articles[Value of ceramide in the diagnosis and risk prediction of coronary artery disease]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3089-3092 Authors: Tu CC, Wan BY, Zhao XL, Li CX, Wu HM, Zhang LL, Li L, Zeng Y Abstract Objective: To evaluate the clinical values of 4 types of ceramides (Cer1, Cer2, Cer3, Cer4) in the coronary artery stenosis, clinical diagnosis and risk prediction. Methods: A total of 890 patients with coronary heart disease...
Related Articles[Application research on carotid arterial shunting during simultaneous coronary artery bypass grafting and carotid endarterectomy]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3085-3088 Authors: Tong ZY, Gu TX, Liu Y, Wang G, Shi EY, Wang C, Mao NH, Jiang DQ, Yu L, Wang HL Abstract Objective: The optimal operative strategy in patients with asymptomatic severe carotid artery stenosis undergoing coronary artery bypass grafting (CABG) is...
Related Articles[Application of combined angiography in diagnosis and treatment of carotid artery stenosis]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3081-3084 Authors: Zhao Y, Jin WT, Zhang YK, Chen XL, Zhao YL, Wang R, Zhang WC, Ye X, Zeng C Abstract Objective: To evaluate the safety and clinical value of combined cardiac and cerebral angiography in the diagnosis and treatment of patients with carotid artery stenosis. Methods: Clinical data of patients...
Related Articles[Simultaneous treatments in patients with severe carotid artery stenosis and coronary artery disease]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3077-3080 Authors: Zhang YK, Zhao Y, Jin WT, Ye X, Chen XL, Zhang WC, Zeng C, Zhao YL, Wang R Abstract Objective: To implement simultaneous treatments in patients with severe carotid artery stenosis and coronary artery disease (CAD), we sought to investigate its efficacy of reducing perioperative...
Related Articles[Safety of carotid endarterectomy for the patiets with carotid artery stenosis and coronary artery disease under dual antiplatelet therapy]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3073-3076 Authors: Jin WT, Zhao Y, Zhang YK, Ye X, Zeng C, Wang R Abstract Objective: To study the safety of dual antiplatelet therapy prior to carotid endarterectomy in the patients with carotid artery stenosis and Coronary Artery Accident. Methods: We...
Related Articles[Endovascular thrombectomy in patients with intracranial large artery occlusion and atrial fibrillation]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3068-3072 Authors: Zhang BR, Liu AH, Mo DP, Huo XC, Liu P, Jin HW, Miao ZR Abstract Objective: To investigate the safety and efficacy of mechanical thrombectomy in patients with atrial fibrillation complicated with acute intracranial arterial occlusion. Methods: Fifty-eight patients with...
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Four dozen drugs were added to the quarterly list after the FDA identified potential signs of serious risk or received new information on a safety issue. Medscape Medical News
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Re: Mao Q, Xia W, Dong G, Chen S, Wang A, Jin G, et al. A nomogram to predict the survival of stage IIIA-N2 non–small cell lung cancer after surgery. J Thorac Cardiovasc Surg. 2018;155:1784-92.
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